Human Immunoglobulin Heavy Constant Gamma 2

Nature

Native

Tag/Conjugate

Unconjugated

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant).

Antigen Description

There are four IgGsubclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance inserum (IgG1 being the most abundant). IgG2 is the only IgG subclass whichpasses through the placenta at a level generally lower than that found in themother. A deficiency of IgG2 indicates a poor antibody response to bacterialpolysaccharides and can lead to increased susceptibility to infections causedby encapsulated bacteria

Keywords

IgG2