The immunogen recognized by this antibody maps to a region between residue 600 and 650 of human insulin receptor substrate 2 using the numbering given in entry NP_003740.2 (GeneID 8660).
IRS2 (insulin receptor substrate 2) is a protein-coding gene. Diseases associated with IRS2 include carbohydrate metabolic disorder, and diabetes mellitus, noninsulin-dependent. GO annotations related to this gene include phospholipid binding and signal transducer activity. An important paralog of this gene is IRS1.
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