Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Pathway
AGE/RAGE pathway; Activation of NF-kappaB in B cells; Acute myeloid leukemia; Adipocytokine signaling pathway
Citations
Publication ()
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COA
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