Anti-IKBKB monoclonal antibody (DCABH-1691) Knockout Validated

Rabbit anti-Human IKBKB monoclonal antibody for WB, IHC-P, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS7154
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide, corresponding to residues at the N terminal of Human IKK beta.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/100 - 1/250; ICC/IF: 1/50 - 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of nuclear factor kappa-B kinase subunit beta; IKK beta; IKK2; IKKB
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Rabbit IgG Isotype Control CABT-B8382 IA Rabbit PDF Inquiry

References


Garimella, SV; Gehlhaus, K; et al. Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. BREAST CANCER RESEARCH 16:-(2014).
Jovanovic, V; Giacomelli, L; et al. AKT1 Leader Gene and Downstream Targets Are Involved in a Rat Model of Kidney Allograft Tolerance. JOURNAL OF CELLULAR BIOCHEMISTRY 111:709-719(2010).

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