Anti-IKBKB monoclonal antibody (DCABH-8540) Knockout Validated

Rabbit anti-Human IKBKB monoclonal antibody for WB, IP

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
Z577
Species Reactivity
Mouse, Human
Immunogen
A synthetic peptide corresponding to residues near the C-term of human IKK-beta.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/5000; Flow Cyt: 1/40; IP: 1/50;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of nuclear factor kappa-B kinase subunit beta; IKK beta; IKK2; IKKB
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Li, W; Li, H; et al. Tumor Necrosis Factor Stimulates Matrix Metalloproteinase 9 Secretion from Cultured Human Chorionic Trophoblast Cells Through TNF Receptor 1 Signaling to IKBKB-NFKB and MAPK1/3 Pathway. BIOLOGY OF REPRODUCTION 83:481-487(2010).
Jovanovic, V; Giacomelli, L; et al. AKT1 Leader Gene and Downstream Targets Are Involved in a Rat Model of Kidney Allograft Tolerance. JOURNAL OF CELLULAR BIOCHEMISTRY 111:709-719(2010).

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