Anti-IGF1 polyclonal antibody [Biotin]

Antibody Isotype

IgG

Species Reactivity

Mouse

Immunogen

E. coli-derived recombinant mouse IGF-I . Gly33-Ala102 Accession Number Q8CAR0

Conjugate

Application Notes

Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-3929 - DPABY-454

Alternative Names

IGF1; insulin-like growth factor 1; Igf-1; Igf-I; C730016P09Rik; insulin-like growth factor I; somatomedin;

Entrez Gene ID

UniProt ID

Antigen Description

Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity. The IGFL (insulin-like growth factor-like) family includes four small (~11 kDa), probably secreted family members in humans and one in mouse. This family shares A and B chain cysteine motifs with the IGF superfamily, and has an additional cysteine motif within an uncleaved region corresponding to the C peptide of the IGF family.

Pathway

AMPK signaling pathway; Adipogenesis; Aldosterone-regulated sodium reabsorption; Androgen Receptor Signaling Pathway; Apoptosis; Dilated cardiomyopathy; Endochondral Ossification; Focal Adhesion;