Product Overview
RecombinantHuman IGF-1 is a single, non-glycosylated, polypeptide chaincontaining 70 amino acids and having a molecular weight of 7,655Da, wasexpressed in E. coli. The sequence of the first five N-terminalamino acids was determined to be Gly-Pro-Glu-Thr-L
Tag/Conjugate
Unconjugated
Format
Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration≥100μg/ml. Further dilutions can be made in other aqueou buffers.
Concentration
1 mg/ml (OD280nm, E0.1%= 0.502) (prior to lyophilization)
Buffer
Lyophilized from50mM acetic acid
Storage
2-8°C short term, -20°C long term
Introduction
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Antigen Description
Insulinis a pancreatic hormone that regulates glucose uptake and the synthesis ofprotein and fat. The insulin like growth factors, isolated from plasma, arestructurally and functionally related to insulin but have a much highergrowth promoting activity. I
Keywords
IGF1; insulin-like growth factor 1 (somatomedin C); IGFI; IGF-I; IGF1A; insulin-like growth factor I; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor IA; insulin-like growth factor IB;
Citations
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