Specifications
Species Reactivity
Human; Mouse; Rabbit; Rat
Immunogen
Purified human IGF1.
Applications
Application Notes
Flow Cytometry (0.5-1 ug/million cells);
Immunofluorescence (1-2 μg/mL);
Immunohistochemistry (1-2 μg/mL for 30 min at RT);
Immunoprecipitation (1-2 ug/500 ug protein);
WB (0.25-0.5 μg/mL) & The optimal working dilution should be determined by the end use
Target
Alternative Names
IGF1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor 1; IGF1A; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; IGFI; IGF-I;
Product Background
Antigen Description
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene
Pathway
Adipogenesis, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;
Citations
Publication ()
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COA
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