Product Overview
Recombinant tuna (Thunnus maccoyii) insulin-like growth factor-I (rtuIGF-I) is a 68 amino acid polypeptide. Tuna IGF-I is synthesized in E. coli using a patented expression system and the tuna IGF-I is correctly folded and then purified by several liquid chromatography purification steps to yield receptor grade tuna IGF-I.
Tag/Conjugate
Unconjugated
Molecular Weight
7,481 Da
Bio-activity
Stimulation of protein synthesis in L6 myoblasts - ED50 < 5 nM
Alternative Names
IGF1; Insulin-like growth factor 1; Igf-1
Purity
> 95 % as determined by HPLC
Format
Lyophilized Powder
Reconstitution
Dissolve in dilute acid (e.g. 10mM HCl or 0.1M acetic acid)
Introduction
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects in adults. IGF-1 is a protein that in humans is encoded by the IGF1 gene. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7,649 Daltons.
Keywords
Insulin-like growth factor 1; IGF1; Hormone
Citations
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