Anti-MSH2 monoclonal antibody (DMAB5548MH)

Mouse anti-Human MSH2 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
26E13
Species Reactivity
Human
Immunogen
BALB/C mice were injected with recombinant human MSH2 protein.
Conjugate
Unconjugated

Target


Alternative Names
MSH2; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); FCC1; COCA1; HNPCC; LCFS2
Entrez Gene ID
UniProt ID

Product Background


Pathway
BRCA1-associated genome surveillance complex (BASC); Colorectal cancer; Direct p53 effectors; Mismatch repair; Pathways in cancer

Citations


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References


Li, ZQ; Scherer, SJ; et al. Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. JOURNAL OF EXPERIMENTAL MEDICINE 200:47-59(2004).
Di Noia, JM; Williams, GT; et al. Dependence of antibody gene diversification on uracil excision. JOURNAL OF EXPERIMENTAL MEDICINE 204:3209-3219(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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