Anti-ODC1 polyclonal antibody

Species Reactivity

Human

Immunogen

Recombinant human ornithine decarboxylase produced in E. coli

Conjugate

Unconjugated

Application Notes

1:500–1:800 using immunofluorescence with overnight incubation at 2oC-8°C.

Alternative Names

ODC1; ornithine decarboxylase; ornithine decarboxylase 1; EC=4.1.1.17; OTTHUMP00000200387; OTTHUMP00000115512; ODC

Entrez Gene ID

4953

UniProt ID

B4DXF8

Antigen Description

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

Pathway

Arginine and proline metabolism; Glutathione metabolism; Metabolic pathways; Metabolism; Metabolism of amino acids and derivatives; Metabolism of polyamines; Polyamine biosynthesis, arginine => ornithine => putrescine; Regulation of ornithine decarboxylase (ODC); Urea cycle and metabolism of amino groups; Validated targets of C-MYC transcriptional activation; putrescine biosynthesis III; superpathway of polyamine biosynthesis II

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More