Specifications
Immunogen
Synthetic peptide: KPDEKYYSSSIWGPTC, corresponding to amino acids 345-360 of Rat Ornithine Decarboxylase.
Target
Alternative Names
ODC1; ornithine decarboxylase 1; ornithine decarboxylase; Ornitine decarboxylase; Odc;
Product Background
Antigen Description
his gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Polyamine biosynthesis, arginine => ornithine =>
Citations
Publication ()
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COA
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