General Notes
This product (Catalog No. DPABH-14980) is a rabbit-derived polyclonal antibody raised against human ODC1, targeting the amino acid region 15–259 of the protein. This antibody exhibits cross-reactivity with Human ODC1 from mouse and rat. It has been affinity purified by Protein A. Ornithine decarboxylase (ODC) is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyzes the decarboxylation of ornithine to form putrescine, representing the first and rate-limiting step in the de novo biosynthesis of polyamines such as spermidine and spermine. These polyamines are small, positively charged organic compounds essential for numerous cellular processes, including DNA replication, gene expression, and protein synthesis. ODC is highly conserved across eukaryotes and plays a critical role in regulating intracellular polyamine levels, which are tightly controlled to support cell growth and proliferation.
DPABH-14980 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-14980 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.