Anti-NCOA1 monoclonal antibody, clone 4643D7b

Antibody Isotype

IgG2b

Clone

4643D7b

Species Reactivity

Human

Immunogen

Recombinant fragment (Human) from an internal region of KAT13A / SRC1.

Conjugate

Alternative Names

NCOA1; nuclear receptor coactivator 1; bHLHe74; F SRC 1; KAT13A; NCoA 1; RIP160; SRC1; NY REN 52 antigen; Protein Hin 2; SRC 1; bHLHe74; Class E basic helix-loop-helix protein 74; F SRC 1; Hin 2 protein; Hin2 protein; MGC129719; MGC129720; mNRC 1; NCoA 1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Pathway

Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem; Metaboli