GeneralInformation
Fusion Species
Mouse X Mouse Hybridoma
Immunological Donor
Female fragile X knock-out (Jackson Lab) Mouse spleen
Cell Line Description
The hybridoma produces monoclonal antibody against Human FMRP
Application Notes
IHC; WB, IHC
CultureMethod
Storage
Liquid nitrogen vapor phase.
Target
Synonyms
FMR1;fragile X mental retardation 1;POF, POF1, premature ovarian failure 1;fragile X mental retardation protein 1;FMRP;FRAXA;MGC87458;protein FMR-1;fragile X mental retardation 1 protein;POF;POF1;NP_001172004;NM_001185075;Q06787;OTTHUMP00000024199;OTTHUMP00000024200;OTTHUMP00000024201;premature ovarian failure 1;Protein FMR-1;OTTHUMP00000024197;HGNC: 3775;Entrez Gene: 2332;Ensembl: ENSG00000102081;OMIM: 309550;UniProtKB: Q06787;FMR1_HUMAN;
Citations
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Say, E; Tay, HG; et al. A Functional Requirement for PAK1 Binding to the KH(2) Domain of the Fragile X Protein-Related FXR1. MOLECULAR CELL 38:236-249(2010).
Tassone, F; Hagerman, RJ; et al. Transcription of the FMR1 gene in individuals with fragile X syndrome. AMERICAN JOURNAL OF MEDICAL GENETICS 97:195-203(2000).