Magic™ Anti-FMR1 (Phospho S499) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Rat

Immunogen

Synthetic peptide corresponding to Rat FMRP (phospho S499).Database link: Q80WE1

Conjugate

Application Notes

WB: 1/1000

Alternative Names

FMR1; fragile X mental retardation 1; FMRP; fragile X mental retardation protein 1 homolog; protein FMR-1; ragile X mental retardation protein; fragile X mental retardation-1 protein; fragile X mental retardation syndrome 1 homolog;

Entrez Gene ID

UniProt ID

Antigen Description

Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

Pathway

RNA transport;