Rabbit Anti-Human FMR1 Polyclonal Antibody (DPABH-24676)

Rabbit Anti-Human FMR1 Polyclonal Antibody for IHC, WB, ICC-IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant Protein, antigen sequence: FKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
Conjugate
unconjugated

Applications


Application Notes
ICC-IF: 1-4 µg/ml
IHC: 1:200 - 1:500
WB: 4 µg/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
Lane 2: Human cell line RT-4
Lane 3: Human cell line U-251 MG

Target


Alternative Names
FMR1; fragile X mental retardation 1; POF; FMRP; POF1; FRAXA
Entrez Gene ID
UniProt ID

Citations


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References


Hessl, D; Dyer-Friedman, J; et al. The influence of environmental and genetic factors on behavior problems and autistic symptoms in boys and girls with fragile X syndrome. PEDIATRICS 108:art. no.-e88(2001).
Achuta, VS; Rezov, V; et al. Tissue Plasminogen Activator Contributes to Alterations of Neuronal Migration and Activity-Dependent Responses in Fragile X Mice. JOURNAL OF NEUROSCIENCE 34:1916-1923(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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