Anti-CD247 (aa 36-54) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to aa 36 –54 aa of the human CD3 zeta protein.

Conjugate

Alternative Names

CD247; CD247 molecule; T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; CD247 antigen, zeta subunit; T-cell receptor T3 zeta chain; CD3Z antigen, zeta polypeptide (TiT3 complex); T-cell antigen receptor co

Entrez Gene ID

UniProt ID

Antigen Description

T-cell surface glycoprotein CD3 zeta chain also known as T-cell receptor T3 zeta chain or CD247 (Cluster of Differentiation 247) is a protein that in humans is encoded by the CD247 gene. The gene is located on the long arm of chromosome 1 at location 1q22-q25 on the Crick (negative) strand. The gene is 87,896 bases in length. The encode protein is 164 amino acids long with a predicted weight of 18.696 kiloDaltons.

Pathway

Adaptive Immune System; CXCR4-mediated signaling events; Chagas disease (American trypanosomiasis); Costimulation by the CD28 family; Downstream TCR signaling; Downstream signaling in naive CD8+ T cells; Generation of second messenger molecules; HIV Infection; HIV-1 Nef: Negative effector of Fas and TNF-alpha; Host Interactions of HIV factors; Natural killer cell mediated cytotoxicity; IL12 signaling mediated by STAT4; PD-1 signaling; T Cell Receptor Signaling Pathway