Anti-CD247 monoclonal antibody (DCABH-362)
Mouse Anti-Mouse CD247 monoclonal antibody for FC, IHC-Fr, WB, ELISA, IP
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113 amino acid synthetic peptide corresponding to the cytoplasmic domain of murine zeta.
Flow Cyt: 1/50 - 1/100; ELISA: 1 μg/ml; IP: 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CD247; CD247 antigen; CD3-zeta/eta; T-cell receptor T3 eta chain; CD3 antigen, zeta polypeptide; T-cell surface glycoprotein CD3 zeta chain
Adaptive Immune System, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Downstream TCR signaling, organism-specific biosystem; Generation of second messenger molecules, organism-specific biosystem; Immune System, organism-specific biosystem;
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Lundholm, M; Mayans, S; et al. Variation in the Cd3 zeta (Cd247) Gene Correlates with Altered T Cell Activation and Is Associated with Autoimmune Diabetes. JOURNAL OF IMMUNOLOGY 184:5537-5544(2010).
Teruel, M; McKinney, C; et al. ASSOCIATION OF CD247 POLYMORPHISMS WITH RHEUMATOID ARTHRITIS: A REPLICATION STUDY AND A META-ANALYSIS. ANNALS OF THE RHEUMATIC DISEASES 72:814-814(2013).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.