Anti-CD247 monoclonal antibody (DMABT-H13268)

Mouse Anti-Human CD247 monoclonal antibody for WB, IHC, IP, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
5B23-G7
Species Reactivity
Human
Immunogen
CD3Z (AAH25703,2a.a. ~275a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CD247; CD247 molecule; CD3Z, CD3z antigen, zeta polypeptide (TiT3 complex) , CD247 antigen; T-cell surface glycoprotein CD3 zeta chain; CD3H; CD3Q
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Disease, organism-specific biosystem; Downstream TCR signaling, organism-specific biosystem;

Citations


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References


Eldor, R; Klieger, Y; et al. CD247, a Novel T Cell-Derived Diagnostic and Prognostic Biomarker for Detecting Disease Progression and Severity in Patients With Type 2 Diabetes. DIABETES CARE 38:113-118(2015).
Recio, M; Aydogmus, C; et al. Complete Deficiency of CD247, the Zeta Chain of the T-Cell Antigen Receptor and the NK Fc Gamma Receptor III. JOURNAL OF CLINICAL IMMUNOLOGY 34:S463-S464(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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