Anti-ATM monoclonal antibody (DMAB5459MH)

Mouse anti-Human ATM monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
TZS7E5
Species Reactivity
Human
Immunogen
BALB/C mice were immunized with synthetic peptide corresponding to human ATM protein amino acids 819-844, conjugated to keyhole limpet hemocyanin.
Conjugate
Unconjugated

Target


Alternative Names
ATM; AT1; ATA; ATC; ATD; ATE
Entrez Gene ID
UniProt ID

Product Background


Pathway
ATM mediated phosphorylation of repair proteins; ATM mediated response to DNA double-strand break; Apoptosis; Autodegradation of the E3 ubiquitin ligase COP1; BARD1 signaling events; BRCA1-associated genome surveillance complex (BASC); Canonical NF-kappaB

Citations


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References


Cheng, QA; Chen, JD; et al. The phenotype of MDM2 auto-degradation after DNA damage is due to epitope masking by phosphorylation. CELL CYCLE 10:1162-1166(2011).
Mori, C; Allen, JW; et al. Completion of meiosis is not always required for acrosome formation in HSP70-2 null mice. BIOLOGY OF REPRODUCTION 61:813-822(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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