Anti-HSPB1 monoclonal antibody (DCABH-440)

Mouse anti-Human HSPB1 monoclonal antibody for WB, IHC-P, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6E8
Species Reactivity
Rat, Human
Immunogen
Purified recombinant fragment of human Hsp27 expressed in E. Coli.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/200 - 1/1000; Flow Cyt: 1/200 - 1/400; ICC/IF: 1/200 - 1/1000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HSPB1; heat shock 27kDa protein 1; heat shock 27kD protein 1; heat shock protein beta-1; Hs.76067; Hsp25
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Gene Expression, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem;

Citations


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References


Guerra, JLL; Wei, QY; et al. Functional promoter rs2868371 variant of HSPB1 associates with radiation-induced esophageal toxicity in patients with non-small-cell lung cancer treated with radio(chemo)therapy. RADIOTHERAPY AND ONCOLOGY 101:271-277(2011).
Maeda, K; Idehara, R; et al. A Family with Distal Hereditary Motor Neuropathy and a K141Q Mutation of Small Heat Shock Protein HSPB1. INTERNAL MEDICINE 53:1655-1658(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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