Anti-HSPB1 monoclonal antibody (DCABH-440)

Mouse anti-Human HSPB1 monoclonal antibody for WB, IHC-P, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6E8
Species Reactivity
Rat, Human
Immunogen
Purified recombinant fragment of human Hsp27 expressed in E. Coli.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/200 - 1/1000; Flow Cyt: 1/200 - 1/400; ICC/IF: 1/200 - 1/1000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HSPB1; heat shock 27kDa protein 1; heat shock 27kD protein 1; heat shock protein beta-1; Hs.76067; Hsp25
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Gene Expression, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem;

Citations


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References


Chalova, AS; Sudnitsyna, MV; et al. Effect of disulfide crosslinking on thermal transitions and chaperone-like activity of human small heat shock protein HspB1. CELL STRESS & CHAPERONES 19:963-972(2014).
Nakhro, K; Park, JM; et al. A novel Lys141Thr mutation in small heat shock protein 22 (HSPB8) gene in Charcot Marie Tooth disease type 2L. NEUROMUSCULAR DISORDERS 23:656-663(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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