Specifications
Species Reactivity
Human, Monkey
Immunogen
Native Human Hsp27 protein.
Applications
Application Notes
Flow Cyt: 50 μg/ml.
Target
Alternative Names
HSPB1; heat shock 27kDa protein 1; heat shock 27kD protein 1; heat shock protein beta-1; Hs.76067; Hsp25; HSP27; HSP28; HSP 27; 28 kDa heat shock protein; heat shock 27 kDa protein; stress-responsive protein 27; estrogen-regulated 24 kDa protein; CMT2F; H
Product Background
Antigen Description
Involved in stress resistance and actin organization.
Pathway
Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Gene Expression, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem;
Citations
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Houlden, H; Laura, M; et al. Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2. NEUROLOGY 71:1660-1668(2008).
Kappe, G; Franck, E; et al. The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10. CELL STRESS & CHAPERONES 8:53-61(2003).
PDF
Certificate of Analysis
