Fusion protein corresponding to a region derived from internal residues of human 3-hydroxymethyl-3-methylglutaryl-CoA lyase
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000 IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-16821) is a rabbit-derived IgG polyclonal antibody raised against human HMGCL. This antibody exhibits cross-reactivity with HMGCL from mouse. It has been affinity purified by protein A. The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. DPABH-16821 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:50–1:200) applications. DPABH-16821 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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