Anti-HMGCL monoclonal antibody (DCABH-282)

Mouse anti-Human HMGCL monoclonal antibody for ICC/IF, ELISA, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
0G6BC0
Species Reactivity
Human
Immunogen
Human liver mitochondria
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 4 μg/ml; In-Cell ELISA: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase; hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; hydroxymethylglutaricaciduria
Entrez Gene ID
UniProt ID

Product Background


Pathway
Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Ketone body metabolism, organism-specific biosystem; Leucine degradation, leucine => acetoacetate + acetyl-CoA, organism-specific biosystem; Leucine degradation, leucine =>

Citations


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References


Montgomery, C; Pei, ZT; et al. Identification and Characterization of an Extramitochondrial Human 3-Hydroxy-3-methylglutaryl-CoA Lyase. JOURNAL OF BIOLOGICAL CHEMISTRY 287:33227-33236(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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