Anti-HDAC1 monoclonal antibody (DCABH-422)

Mouse anti-Human HDAC1 monoclonal antibody for WB, FC, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
6D4
Species Reactivity
Rat, Human, Monkey
Immunogen
Recombinant full length HDAC1 produced in HEK293T cells (Human) (NP_004955)
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/200 - 1/500; Flow Cyt: 1/100; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HDAC1; histone deacetylase 1; RPD3L1; GON 10; HD1; reduced potassium dependency, yeast homolog-like 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem;

Citations


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References


Sugimoto, T; Tomita, A; et al. Escape mechanisms from antibody therapy to lymphoma cells: Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 390:48-53(2009).
Kikuchi, H; Yamashita, K; et al. Lacking of Aiolos accelerates pre-mature B cell apoptosis mediated by BCR signaling through elevation in cytochrome c release. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1793:1304-1314(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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