Rabbit Anti-Human GPHN (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

A synthesized peptide derived from human GPHN, corresponding to a region within the internal amino acids.

Conjugate

Application Notes

WB 1:1000-3000
IHC 1:50-1:200

General Notes

This product (Catalog No. DPABH-27926) is a rabbit-derived polyclonal antibody raised against human GPHN. This antibody exhibits cross-reactivity with GPHN from mouse. It has been affinity purified by Protein A. Enables several functions, including identical protein binding activity; molybdopterin adenylyltransferase activity; and molybdopterin molybdotransferase activity. Involved in establishment of protein localization; neurotransmitter receptor localization to postsynaptic specialization membrane; and synapse assembly. Acts upstream of or within Mo-molybdopterin cofactor biosynthetic process. Located in several cellular components, including GABA-ergic synapse; cytoplasmic side of plasma membrane; and inhibitory synapse. Is active in glycinergic synapse and postsynaptic specialization, intracellular component. Human ortholog(s) of this gene implicated in inherited metabolic disorder and molybdenum cofactor deficiency type C. Orthologous to human GPHN (gephyrin).
DPABH-27926 is suitable for use in WB 1 (1000-3000), IHC 1 (50-1:200) applications.
DPABH-27926 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID