Anti-GLUL (aa 274-373) polyclonal antibody

Species Reactivity

Human

Immunogen

GLUL (NP_002056, 274 a.a. ~ 373 a.a) partial recombinant protein with GST tag. The sequence is IEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEK KGYFEDRRPSANCDPFSVTEALIRTCLLNETGDEPFQYKN

Conjugate

Alternative Names

GLUL; glutamate-ammonia ligase; GS; GLNS; PIG43; PIG59; glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]

Pathway

Alanine, aspartate and glutamate metabolism; Amino acid synthesis and interconversion (transamination); Arginine and proline metabolism; Biosynthesis of amino acids