Tag/Conjugate
Unconjugated
Purity
> 95 % by SDS-PAGE.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Reconstitution
Mouse peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.
Introduction
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
Synonyms
GLUL; glutamate-ammonia ligase; GS; GLNS; PIG43; PIG59; glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59;
Citations
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Dimitrova, K; Stoehr, M; et al. Overexpression of the Hedgehog Signalling Pathway in Head and Neck Squamous Cell Carcinoma. ONKOLOGIE 36:279-+(2013).
Laht, S; Meerits, K; et al. Generation and characterization of a single-chain Fv antibody against Gli3, a hedgehog signaling pathway transcription factor. HYBRIDOMA 27:167-174(2008).