This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.
Pathway
Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Astrocytic Glutamate-Glutamine Uptake And Metabolism, organism-specific biosystem; GABAergic synapse, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Tagariello, A; Luther, J; et al. Ucma - A novel secreted factor represents a highly specific marker for distal chondrocytes. MATRIX BIOLOGY 27:3-11(2008).
Laht, S; Meerits, K; et al. Generation and characterization of a single-chain Fv antibody against Gli3, a hedgehog signaling pathway transcription factor. HYBRIDOMA 27:167-174(2008).
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