Anti-GLUL monoclonal antibody, clone 7/H

Antibody Isotype

IgG2a

Clone

7/H

Species Reactivity

Sheep

Immunogen

Full length protein, corresponding to amino acids 1-373 of Sheep Glutamine Synthetase.

Conjugate

Alternative Names

GLUL; glutamate-ammonia ligase; GLNS, glutamate ammonia ligase (glutamine synthase); glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59;

Entrez Gene ID

UniProt ID

Antigen Description

This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.

Pathway

Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Astrocytic Glutamate-Glutamine Uptake And Metabolism, organism-specific biosystem; GABAergic synapse, organism-specific biosystem;