Anti-GLUL monoclonal antibody, clone FQS24133(C)

Antibody Isotype

IgG

Clone

FQS24133(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Glutamine Synthetase aa 250-350 (Cysteine residue). The exact sequence is proprietary.Database link: P15104

Conjugate

Application Notes

WB: 1/1000 - 1/5000; IHC-P: 1/100 - 1/250; IP: 1/10 - 1/100; Flow Cyt: 1/10 - 1/100;

Alternative Names

GLUL; glutamate-ammonia ligase; GLNS, glutamate ammonia ligase (glutamine synthase); glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59;

Entrez Gene ID

UniProt ID

Antigen Description

This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.

Pathway

Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Astrocytic Glutamate-Glutamine Uptake And Metabolism, organism-specific biosystem; GABAergic synapse, organism-specific biosystem;