General Notes
This product (Catalog No. DPABH-29101) is a rabbit-derived polyclonal antibody raised against human FTH1, targeting the amino acid region 2–183 of the protein. This antibody exhibits cross-reactivity with Human FTH1 from rat. It has been affinity purified by Protein A. FTH1 (ferritin heavy chain 1), located on chromosome 11q12.3, is a gene that encodes the heavy subunit of ferritin, the primary intracellular protein responsible for storing iron in a soluble, non-toxic form across prokaryotes and eukaryotes. This subunit plays a crucial role in iron homeostasis by facilitating the oxidation of ferrous iron (Fe²⁺) to ferric iron (Fe³⁺) through its ferroxidase activity, enabling safe sequestration within the ferritin mineral core and preventing oxidative damage from free iron.
DPABH-29101 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-29101 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.