Specifications
Immunogen
This clone has been derived from hybridization of SP2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified human ferritin.
Applications
Application Notes
IHC/IF: 1 μg/ml.
Target
Alternative Names
FTH1; ferritin heavy chain 1; ferritin heavy chain; H-ferritin; ferritin H subunit; FHC; Fth; HFt; MFH; AL022624; AL033366;
Product Background
Antigen Description
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
Pathway
Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Iron Homeostasis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem;
Citations
Publication ()
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