Anti-FURIN monoclonal antibody, clone FQS25785

Antibody Isotype

IgG

Clone

FQS25785

Species Reactivity

Mouse; Rat; Human

Immunogen

Recombinant fragment within Human Furin aa 200-350. The exact sequence is proprietary.Database link: P09958

Conjugate

Application Notes

ICC/IF: 1/250; IHC-P: 1/50; WB: 1/1000 - 1/10000.

Alternative Names

FURIN; furin (paired basic amino acid cleaving enzyme); FUR, PACE, paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) , PCSK3; furin; SPC1; FES upstream region; dibasic processing enzyme; dibasic-processing enzyme; furi

Entrez Gene ID

UniProt ID

Antigen Description

Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.

Pathway

Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem; Glypican 3 network, organism-specific biosystem.