Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
Pathway
Activation of Matrix Metalloproteinases; Degradation of the extracellular matrix; Delta-Notch Signaling Pathway; Developmental Biology; Extracellular matrix organization; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins; Glypican 3
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