Mouse myeloma cell line NS0-derived recombinant human Furin. Asp108-Glu715 Accession Number NP_002560
Conjugate
Unconjugated
Applications
Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4072 - DPABY-681
This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.
Pathway
Activation of Matrix Metalloproteinases; Assembly Of The HIV Virion; Collagen degradation; Degradation of the extracellular matrix; Delta-Notch Signaling Pathway; Developmental Biology; Disease; Elastic fibre formation;
Citations
Publication ()
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