This gene encodes a FERM and PDZ domain-containing protein and is located in a region of chromosome 10q which contains a segmental duplication resulting in three nearly identical regions. This copy of the gene is full-length and is in the telomeric duplicated region. The exact function of this gene is unknown; however, FERM domains often play a role in signal transduction pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Stenzel, N; Fetzer, CP; et al. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. JOURNAL OF CELL SCIENCE 122:3374-3384(2009).
Lipinski, S; Grabe, N; et al. RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:21426-21431(2012).
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