A synthetic peptide corresponding to N-terminus 15 amino acids of human FRMPD2.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1-2 μg/mL. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
FRMPD2; FERM and PDZ domain containing 2; PDZK4; PDZD5C; PDZK5C; FERM and PDZ domain-containing protein 2; PDZ domain containing 5C; PDZ domain-containing protein 4;
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants.
Citations
Publication ()
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