Human FRMPD2 blocking peptide (CDBP1297)

Synthetic Human FRMPD2 blocking peptide for BL

Product Overview
Blocking peptide for anti-FRMPD2 antibody
Target
FRMPD2
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants.
Function
1-phosphatidylinositol binding; protein binding;
Synonyms
FRMPD2; FERM and PDZ domain containing 2; PDZ domain containing 5C , PDZD5C, PDZK5C; FERM and PDZ domain-containing protein 2; MGC35285; PDZ domain containing 5C; PDZ domain-containing protein 4; PDZK4; PDZD5C; PDZK5C; MGC87776; MGC87777; MGC90186; MGC178184; MGC178187;

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References


Stenzel, N; Fetzer, CP; et al. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. JOURNAL OF CELL SCIENCE 122:3374-3384(2009).
Lipinski, S; Grabe, N; et al. RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:21426-21431(2012).

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