Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Pathway
Arginine and proline metabolism; D-Arginine and D-ornithine metabolism; Glycine, serine and threonine metabolism; Glyoxylate metabolism
Citations
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