Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)
Applications
Application Notes
WB: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250.
Target
Alternative Names
DAO; D-amino-acid oxidase; DAMOX; D-amino acid oxidase; DAAO; OXDA; MGC35381;
Product Background
Antigen Description
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; D-Arginine and D-ornithine metabolism, organism-specific biosystem; D-Arginine and D-ornithine metabolism, conserved biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem; Glyoxylate metabolism, organism-specific biosystem;
Citations
Publication ()
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COA
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