Anti-CXCL3 polyclonal antibody [Biotin]

Antibody Isotype

IgG

Species Reactivity

Rat

Immunogen

E. coli-derived recombinant rat CXCL3/CINC-2 alpha/beta . Arg33-Ser100 Accession Number Q10746

Conjugate

Application Notes

Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4258 - DPABY-704

Alternative Names

CXCL3; chemokine (C-X-C motif) ligand 3; Cinc2; Cinc-2; Gm1960; C-X-C motif chemokine 3; MIP2-alpha/beta; macrophage inflammatory protein 2-alpha/beta; cytokine-induced neutrophil chemoattractant 2; cytokine-induced neutrophil chemoattractant-2;

Entrez Gene ID

UniProt ID

Antigen Description

CXCL3/GRO gamma, also known as DCIP-1 in mouse and CINC-2 in rat, is a member of the CXC chemokine family. Human CXCL3/GRO gamma is 107 amino acids (aa) in length, which includes a proposed signal peptide (aa 1–34), with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 65% and 59% aa sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl1 gene is homologous to human CXCL3/GRO gamma protein. CXCL3/GRO gamma is chemotactic for granulocytes, including neturophils.

Pathway

Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokines and Inflammatory Response (BioCarta); G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; Legionellosis;