E. coli-derived recombinant rat CXCL3/CINC-2 alpha/beta . Arg33-Ser100 Accession Number Q10746
Conjugate
Unconjugated
Applications
Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4258 - DPABY-704
CXCL3/GRO gamma, also known as DCIP-1 in mouse and CINC-2 in rat, is a member of the CXC chemokine family. Human CXCL3/GRO gamma is 107 amino acids (aa) in length, which includes a proposed signal peptide (aa 1–34), with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 65% and 59% aa sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl1 gene is homologous to human CXCL3/GRO gamma protein. CXCL3/GRO gamma is chemotactic for granulocytes, including neturophils.
Pathway
Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokines and Inflammatory Response (BioCarta); G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; Legionellosis;
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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Lindberg, J; af Klint, E; et al. Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients. ARTHRITIS RESEARCH & THERAPY 8:-(2006).
Hamid, C; Norgate, K; et al. Anti-beta 2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome. ANNALS OF THE RHEUMATIC DISEASES 66:1000-1007(2007).
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COA
Certificate of Analysis
