General Notes
This product (Catalog No. DPABH-16189) is a rabbit-derived IgG polyclonal antibody raised against human CHRNE, targeting the amino acid region 111–210 of the protein. This antibody exhibits cross-reactivity with CHRNE from mouse and rat. It has been affinity purified by Protein A. Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
DPABH-16189 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500), ICC/IF (1:100–1:500), ELISA (1:5,000–1:10,000) applications.
DPABH-16189 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
Nicotinic Acetylcholine Receptor epsilon; Acetylcholine receptor subunit epsilon; ACHE_HUMAN; AchR epsilon subunit; ACHRE; Cholinergic receptor, nicotinic, epsilon polypeptide; Chrne; CMS1D; CMS1E; CMS2A; FCCMS; SCCMS
COA
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