Anti-CHRNE monoclonal antibody

Antibody Isotype

IgG2a

Species Reactivity

Human

Immunogen

Recombinant fragment, corresponding to amino acids 21-131 of Human Nicotinic Acetylcholine Receptor epsilon

Conjugate

Alternative Names

CHRNE; cholinergic receptor, nicotinic, epsilon (muscle); cholinergic receptor, nicotinic, epsilon; acetylcholine receptor subunit epsilon; acetylcholine receptor; nicotinic; epsilon (muscle); ACHRE; AchR epsilon subunit; acetylcholine receptor, nicotinic

Entrez Gene ID

UniProt ID

Antigen Description

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Pathway

Acetylcholine Binding And Downstream Events, organism-specific biosystem; Activation of Nicotinic Acetylcholine Receptors, organism-specific biosystem; ErbB2/ErbB3 signaling events, organism-specific biosystem; Highly sodium permeable acetylcholine nicotinic receptors, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; Neuronal System, organism-specific biosystem;