Anti-CHEK2 monoclonal antibody (DCABH-410)
Mouse anti-Human CHEK2 monoclonal antibody for WB, FC, ICC/IF
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Rat, Dog, Human, Monkey
Recombinant full length Human Chk2 protein produced in HEK293T cells (NP_009125).
WB: 1/500 - 1/1000; Flow Cyt: 1/100; ICC/IF: 1/50 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CHEK2; checkpoint kinase 2; CHK2 (checkpoint, S.pombe) homolog , CHK2 checkpoint homolog (S. pombe) , RAD53; serine/threonine-protein kinase Chk2; bA444G7; CDS1
Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; FOXM1 transcription factor network, organism-specific biosystem; G1/S DNA Damage Checkpoints, organism-specific biosystem;
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van Puijenbroek, M; van Asperen, CJ; et al. Homozygosity for a CHEK2* 1100delC mutation identified in familial colorectal cancer does not lead to a severe clinical phenotype. JOURNAL OF PATHOLOGY 206:198-204(2005).
Ribeiro-Silva, A; Moutinho, MAK; et al. Expression of checkpoint kinase 2 in breast carcinomas: correlation with key regulators of tumor cell proliferation, angiogenesis, and survival. HISTOLOGY AND HISTOPATHOLOGY 21:373-382(2006).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.