Anti-CHEK2 monoclonal antibody (DMABT-H13431)

Mouse anti-Human CHEK2 monoclonal antibody for WB, IHC, IF, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
5C8
Species Reactivity
Human
Immunogen
CHEK2 (AAH04207.1,2a.a. ~ 543 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CHEK2; checkpoint kinase 2; CHK2 (checkpoint, S.pombe) homolog , CHK2 checkpoint homolog (S. pombe) , RAD53; serine/threonine-protein kinase Chk2; bA444G7; CDS1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; FOXM1 transcription factor network, organism-specific biosystem; G1/S DNA Damage Checkpoints, organism-specific biosystem;

Citations


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References


Nishimura, J; Dewa, Y; et al. Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats. ARCHIVES OF TOXICOLOGY 82:641-654(2008).
van Puijenbroek, M; van Asperen, CJ; et al. Homozygosity for a CHEK2* 1100delC mutation identified in familial colorectal cancer does not lead to a severe clinical phenotype. JOURNAL OF PATHOLOGY 206:198-204(2005).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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