KLH conjugated synthetic peptide corresponding to a region within internal amino acids 642-671 of Human CACNA2D2 (NP_001167522.1, NP_001005505.1, Q9NY47).
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G). Overexpression induces apoptosis.
Pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cardiac muscle contraction; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels; Dilated cardiomyopathy;
Citations
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