Characteristics of primary glomerular diseases patients with hematuria in Turkey: the data from TSN-GOLD Working Group
INTERNATIONAL UROLOGY AND NEPHROLOGY
Authors: Sumnu, Abdullah; Turkmen, Kultigin; Cebeci, Egemen; Turkmen, Aydin; Eren, Necmi; Seyahi, Nurhan; Oruc, Aysegul; Dede, Fatih; Derici, Ulver; Basturk, Taner; Sahin, Garip; Sipahioglu, Murat; Sahin, Gulizar Manga; Tatar, Erhan; Dursun, Belda; Sipahi, Savas; Yilmaz, Murvet; Suleymanlar, Gultekin; Ulu, Sena; Gungor, Ozkan; Kutlay, Sim; Bahcebasi, Zerrin Bicik; Sahin, Idris; Kurultak, Ilhan; Sevinc, Can; Yilmaz, Zulfikar; Kazancioglu, Rumeyza Turan; Cavdar, Caner; Candan, Ferhan; Aydin, Zeki; Oygar, Deren; Gul, Bulent; Altun, Bulent; Paydas, Saime; Uzun, Sami; Istemihan, Zulal; Ergul, Metin; Dincer, Mevlut Tamer; Gullulu, Mustafa; Piskinpasa, Serhan; Akcay, Omer Faruk; Unsal, Abdulkadir; Koyuncu, Sumeyra; Gok, Mahmut; Ozturk, Savas
Abstract
Purpose Hematuria is one of the most common laboratory findings in nephrology practice. To date, there is no enough data regarding the clinical and histopathologic characteristics of primary glomerular disease (PGD) patients with hematuria in our country. Methods Data were obtained from national multicenter (47 centers) data entered into the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) database between May 2009 and June 2019. The data of all PGD patients over the age of 16 years who were diagnosed with renal biopsy and had hematuria data were included in the study. Demographic characteristics, laboratory and biopsy findings were also recorded. Results Data of 3394 PGD patients were included in the study. While 1699 (50.1%) patients had hematuria, 1695 (49.9%) patients did not have hematuria. Patients with hematuria had statistically higher systolic blood pressure, serum blood urea nitrogen, creatinine, albumin, levels and urine pyuria. However, these patients had statistically lower age, body mass index, presence of hypertension and diabetes, eGFR, 24-h proteinuria, serum total, HDL and LDL cholesterol, and C3 levels when compared with patients without hematuria. Hematuria was present 609 of 1733 patients (35.8%) among the patients presenting with nephrotic syndrome, while it was presented in 1090 of 1661 (64.2%) patients in non-nephrotics (p < 0.001). Conclusion This is the first multicenter national report regarding the demographic and histopathologic data of PGD patients with or without hematuria. Hematuria, a feature of nephritic syndrome, was found at a higher than expected in the PGDs presenting with nephrotic syndrome in our national database.
C3 and C4 Grass Species: Who Can Reduce Soil Nitrous Oxide Emissions in a Continental Arid Region?
ATMOSPHERE
Authors: Ning, Jiao; He, Xiong Z.; Hou, Fujiang
Abstract
In order to relieve grazing pressure, drought-tolerant grass species are widely cultivated in arid regions. However, soil N emission is largely neglected while pursuing forage yield. We carried out a randomized block study to investigate whether and how the C3 and C4 grass species differ in soil N emission in a typical salinized field with temperate continental arid climate in the northwest inland regions, China. We quantified soil N2O flux from two C3 (barley and rye) and two C4 grass species [corngrass and sorghum hybrid sudangrass (SHS)] in fields during the growing season (from May to September) by using the static box method, and then determined the relationships between soil N2O fluxes and forage yield and soil properties. Results show that soil available nitrogen, soil temperature, pH, soil organic carbon, and total nitrogen were correlated, but soil water was anti-correlated with soil N2O fluxes. In addition, N2O flux increased significantly faster with soil temperature in C4 than in C3 grass fields. Although the lower total N2O emission fluxes were detected for C3 species, the lower yield-scaled N2O was detected for C4 species. Our study provided insights into the determination of grass species and the understanding of mechanisms regulating N2O fluxes in C3 and C4 species in the continental arid regions.