Anti-Amphetamine monoclonal antibody, clone N68750

Adopting a multi-agent systems paradigm, we developed, tested and exploited a computational testbed that simulates gathering features of the social amoeba Dictyostelium discoideum. It features a tailored design and implementation to manage discrete simulations with autonomous agents on a microscopic scale, thus focusing on their social behavior and mutual interactions. Hence, we could assess the behavioral conditions under which decentralized gathering could occur. We investigated the dependence of the model dynamics on the main physical variables, namely density and number of amoebas, gaining indications that the process strongly depends on both. This result integrates previous researches, where density is identified as the sole relevant variable. We determined a high-density and high-numerosity region where assuming a scale-free behavior is safe. We also estimated the systematic uncertainties arising from a number of amoebas off the scale-free region, when coping with limited computational resources. Finally, we probed the robustness of the simulated gathering process against both extrinsic and intrinsic noise sources.

Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and they are an important part of the innate immune system of different organisms. AMPs have a wide range of inhibitory effects against bacteria, fungi, parasites and viruses. The emergence of antibiotic-resistant microorganisms and the increasing of concerns about the use of antibiotics resulted in the development of AMPs, which have a good application prospect in medicine, food, animal husbandry, agriculture and aquaculture. This review introduces the progress of research on AMPs comprehensively and systematically, including their classification, mechanism of action, design methods, environmental factors affecting their activity, application status, prospects in various fields and problems to be solved. The research progress on antivirus peptides, especially anti-coronavirus (COVID-19) peptides, has been introduced given the COVID-19 pandemic worldwide in 2020.